Nationally, he directs the MRC Health eResearch Centre of the UK’s Farr Institute for Health Informatics Research (www.herc.ac.uk) and originated the Connected Health Cities UK network of learning health systems. He holds qualifications in Clinical Medicine, Pharmacology, Biostatistics, Public Health and Health Informatics, and leads a multi-disciplinary team developing and applying health data science methodology. He also writes software (e.g. www.statsdirect.com). Internationally, he is a Fellow of the American College of Medical Informatics and works through WHO, IMIA and other networks towards toward a future of more globally interoperable modelling with large-scale health data – for discovery science, for actionable analytics in health systems, and for citizen-driven healthcare.