ChIP-sequencing, also known as ChIP-seq, is a method used primarily to determine how transcription factors and other chromatin-associated proteins influence phenotype-affecting mechanisms.
Determining how proteins interact with DNA to regulate gene expression is essential for fully understanding many biological processes and disease states. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins.
High quality library preparation is key to a successful ChIP-seq experiment. Written by scientists with many years of experience of ChIP assay development, the new document provides an informative 10-point illustrated guide to help you improve your ChIP-seq library preparation.
To download a pdf version, or request a hard copy, of this new guide please visit www.chromatrap.com/uploads/documents/Top10-Tips-for-ChIP-Seq-Library-Prep_print.pdf.