PATHM2 libraries are available to identify accessory molecules that improve cell viability, proliferation or yields. All compounds are hand selected to address ‘traditional’ cascades that play a role in pluripotency maintenance or specific differentiation. Multiple agents are included to interrogate new and emerging networks/targets relevant to stem cell biology.
PATHM2 kits are also available to screen your disease model and identify/confirm critical pathways and targets. Using PATHM2 kits you will be able to find disease state modulators as starting points for further refinement.
All small molecule compounds in the kits have drug/lead-like properties, good water solubility, biomembrane permeability, activity/selectivity profile and potential for optimization. AMSBIO also provide one-stop scale-up, medicinal chemistry, screening and development services.
In addition, PATHM2 kits can be used to study selected signalling pathways of interest. Custom sets are available to identify more selective and potent small molecules to replace inferior but still commonly used ones. For further information, click here.