ClinigenClinigen Group plc and Pharming Group NV  have entered into an international global access collaboration for HAEi, the International Patient Organization for C1- Inhibitor Deficiencies.

The “HAEi GAP” will provide access to RUCONEST (conestat alfa) to eligible patients with hereditary angioedema (HAE), who currently do not have access to effective medication to treat acute attacks of the disease.

HAEi GAP is the first global access programme for HAE and the first to be driven by a patient organization. The programme enables patients in countries where RUCONEST is not commercially available to gain access to the drug through an ethical and regulatory compliant “Named Patient Program” mechanism.

“HAEi is committed to securing access to HAE medications for patients across the globe,” said Anthony J. Castaldo, President of HAEi. “We are extremely proud to have established HAEi GAP with our current partners and will continue to work with other manufacturers with the hope of expanding the programme in the future.”

Simon Estcourt, Managing Director, Managed Access Programmes, Clinigen Group said: “HAEi’s groundbreaking programme will ensure that HAE sufferers worldwide can gain access to effective and potentially life-saving treatment. Our secure supply chain and regulatory expertise will enable us to work closely with Pharming to supply patients with RUCONEST ethically and legitimately, removing the need and the risk for patients to resort to other less reliable or even illegal sources of the drug. We look forward to working with both HAEi and Pharming on this unique project.”

Sijmen de Vries, CEO, Pharming said: “We are delighted to be the first partners of HAEi and to initiate this programme by providing access to RUCONEST, a recombinant human C1- inhibitor, approved by EMA and FDA for the treatment of acute attacks of HAE in patients. In this way we can help to improve the lives of those HAE patients that otherwise would continue suffering from this debilitating and unpredictable disease.”