Cambrex Corporation, the leading manufacturer of small molecule innovator and generic active pharmaceutical ingredients (APIs), has expanded its large-scale manufacturing capacity at its cGMP facility in Karlskoga, Sweden, and has introduced additional continuous flow manufacturing for the production of high purity intermediates.
The expansion includes the installation of new multipurpose reactors ranging from 4–12 m3 and upgrading of the control room within an existing plant on site.
This extra capacity increases the large-scale manufacturing capabilities of the Karlskoga facility, which supports clients’ development projects from R&D through to large scale commercial manufacturing. Installation of all new equipment, including a 9 m³ hydrogenation reactor, is expected to be completed by Q3 2017.
In addition to the capacity investment at the Karlskoga site, Cambrex has introduced a dedicated continuous flow production unit, capable of producing multiple metric tons of high purity intermediates per annum.
“The additional capacity at the site, within our current infrastructure, will enable us to service our existing and future customers more efficiently,” commented Bjarne Sandberg, Managing Director, Cambrex Karlskoga.
He added; “The continuous flow unit builds on our long experience with continuous flow and high energy chemistry and allows for greater production efficiency and flexibility.”
The expansion at Cambrex’s Swedish site is part of an ongoing strategic campaign to invest in small molecule API manufacturing across its global network of facilities.